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Bepridil hydrochloride

CAS No. 68099-86-5

Bepridil hydrochloride( CERM 1978 )

Catalog No. M20140 CAS No. 68099-86-5

Bepridil is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX) sodium channels and cardiac sarcolemmal KATP channels.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bepridil hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Bepridil is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX) sodium channels and cardiac sarcolemmal KATP channels.
  • Description
    Bepridil is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX) sodium channels and cardiac sarcolemmal KATP channels.(In Vitro):Bepridil hydrochloride is a calcium channel blocker, with antianginal activity.(In Vivo):Bepridil hydrochloride (21 mg/kg) reduces heart rate and mean arterial pressure, decreases the mean coronary vascular resistance and increases stroke volume in rats.
  • In Vitro
    Bepridil hydrochloride is a calcium channel blocker, with antianginal activity.
  • In Vivo
    Bepridil hydrochloride (21 mg/kg) reduces heart rate and mean arterial pressure, decreases the mean coronary vascular resistance and increases stroke volume in rats.
  • Synonyms
    CERM 1978
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel
  • Research Area
    Cardiovascular Disease
  • Indication
    Angina pectoris; Tachycardia

Chemical Information

  • CAS Number
    68099-86-5
  • Formula Weight
    403
  • Molecular Formula
    C24H35ClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 130 mg/mL (322.58 mM)
  • SMILES
    Cl.CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Flaim SF et al. Effects of bepridil hydrochloride on cardiocirculatory dynamics coronary vascular resistance and cardiac output distribution in normal conscious rats. J Cardiovasc Pharmacol. 1988 Mar;11(3):363-72.
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